Pelger-Huet anomaly

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Pelger-Huet anomaly

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Author: Teresa Kraus
Category: Morphologic variants of normal cells > Morphologic variants of white blood cells > Neutrophil > Abnormal neutrophils > True Pelger Huet
Published Date: 09/17/2015

Pelger-Huet anomaly is a congenital autosomal dominant anomaly in which neutrophil nuclei fail to segment normally. In homozygotes , the nucleus is round. In heterozygotes, most granulocytes have bilobed nuclei ("pince-nez" cells) resembling bands.

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