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Chronic lymphocytic leukemia with flowcytometry 1

Chronic lymphocytic leukemia with flowcytometry 1
#00065965
Author: Dr. Madhura Jogwar; Dr. Sumitha Baskaran; Dr. Namrata Singh; Dr. Sanjay Gohil; Metropolis Healthcare Ltd; Dr. Abhay Bhave; Dr. Shrinath Kshirsagar; Gleneagles Hospital, Mumbai
Category: Lymphoma: Mature B-cell and Plasma cell Neoplasms > Low-grade B-cell lymphoma > Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Published Date: 11/20/2025

Images showing Microscopic findings of  74 % lymphocytes along with smudge cells and atypical lymphocytes. Lymphocytes were small with condensed chromatin having a soccer ball or a cracked earth appearance. Cytoplasm was scant.

 Flow cytometry : Cd45/side scatter plot showed 75 %cell events in lymphocyte window. Of these gated cells,78 % were positive for CD19 & show following expression of markers : CD5 positive moderate, CD20 positive moderate, CD23 positive moderate, CD200 positive moderate. CD19/CD5 co-expression was seen in 95% of these cells. This was suggestive of B-cell chronic lymphocytic leukemia (B-CLL)

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