A 73/M developed dragging splenomegaly and pancytopenia which led to a marrow biopsy. A positive T-cell gene rearrangement PCR was noted but the morphologic and immunophenotypic features were inconsistent for a T-cell lymphoma. A second opinion was sought and the findings below illustrate a typical case of T-cell/histiocyte rich large B-cell lymphoma involving the marrow.

Progressed forms of NLPHL rich in T-cell often overlap with cases of T/HRBCL and many think of these two entities to be two ends of a spectrum with a continuum of histologic features that overlap between the two entities.

This case bears resemblance to a series of similar cases of the so-called "micronodular" variant of T-cell/histiocyte rich large B-cell lymphoma described by Drs. Burke and Dogan.